protein

CALB1PROTEIN

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about CALB1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Calbindin Calbindin D 28K is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	CALB1PROTEIN
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	neurons throughout the central nervous system, particularly in Purkinje cells of the [cerebellum]
Molecular Weight	30 kDa
GeneCards	CALB1PROTEIN
Human Protein Atlas	CALB1PROTEIN
Early Marker	Loss of calbindin is an early marker of neuronal dysfunction
Selective Vulnerability	Calbindin+ neurons show relative resistance to amyloid-beta toxicity
Associated Diseases	Als, Alzheimer, Inflammation, Ms
Interactions	ALZHEIMER, APOE, APP, ASTROCYTES, Bdnf, BDNF
KG Connections	140 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Calbindin - Calbindin D-28k

protein · 750 words

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Pathway Diagram

graph TD
    CALB1PROTEIN["CALB1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    CALB1PROTEIN -->|"implicated_in"| neurodegeneration
    style CALB1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CALB1PROTEIN in their description or question text

No additional research found