CAPRIN1

Understanding Entity Pages

This page aggregates everything SciDEX knows about CAPRIN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CAPRIN1 encodes a RNA-binding protein critical for stress granule formation, mRNA transport, and translational control. CAPRIN1 is implicated in ALS, FTD, and potentially Alzheimer's disease through its role in RNA metabolism and protein aggregation.

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graph TD
    CAPRIN1["<b>CAPRIN1</b>"]
    Als{"Als"}
    CAPRIN1 -->|"interacts with"| Als
    CAPRIN1 -->|"activates"| Als
    Autism{"Autism"}
    CAPRIN1 -->|"associated with"| Autism
    Ms{"Ms"}
    CAPRIN1 -->|"activates"| Ms
    G3BP2["G3BP2"]
    CAPRIN1 -->|"interacts with"| G3BP2
    G3BP1["G3BP1"]
    CAPRIN1 -->|"protects against"| G3BP1
    Oxidative_Stress(["Oxidative Stress"])
    CAPRIN1 -->|"activates"| Oxidative_Stress
    Synaptic_Plasticity(["Synaptic Plasticity"])
    CAPRIN1 -->|"regulates"| Synaptic_Plasticity
    neurodegeneration["neurodegeneration"]
    CAPRIN1 -->|"implicated in"| neurodegeneration
    style CAPRIN1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0