gene 1,472 words KG: CAPRIN1 2026-03-27
kind:genesection:genesstate:published
Contents

CAPRIN1 Gene

🧬 Gene Info
Gene SymbolCAPRIN1
Full NameCell Cycle Associated Protein 1
Chromosome11p13
Functionencodes an RNA-binding protein that plays critical roles in stress granule formation, mRNA transport, and translational regulation.
Primary Expressionvarious brain regions:
Molecular Weight78 kDa
Amino Acids709 aa
Exons17
PathwaysSynaptic Plasticity
UniProt IDQ14444
NCBI Gene ID9908
Ensembl IDENSG00000135387
OMIM608157
GeneCardsCAPRIN1
Human Protein AtlasCAPRIN1
Associated DiseasesAutism
InteractionsG3BP2
KG Connections9 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (10)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Phase-Separated Organelle Targeting
Score: 0.52
Stress Granule Phase Separation Modulators
Score: 0.49
RNA Granule Nucleation Site Modulation
Score: 0.48
Cryptic Exon Silencing Restoration
Score: 0.46

Related Analyses (7)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

Proposed experiment from debate on TDP-43 undergoes liquid-l
falsification · proposed · Score: 0.40

See Also (4)

Packard Center for ALS Research
institution · KG edge: activates
G3BP2 - Ras-GTPase-Activating Protein-Binding Protein 2
gene · KG edge: interacts_with
G3BP1
gene · KG edge: protects_against
Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (9 edges)

CAPRIN1 interacts_with G3BP2
CAPRIN1 protects_against G3BP1
CAPRIN1 interacts_with Als
CAPRIN1 activates Als
CAPRIN1 associated_with Autism
CAPRIN1 activates Ms
CAPRIN1 activates Oxidative Stress
CAPRIN1 regulates Synaptic Plasticity
CAPRIN1 participates_in synaptic plasticity