concept

CENPN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CENPN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

18Connections

0Hypotheses

0Analyses

15Outgoing

3Incoming

0Experiments

0Debates

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💡 Concept Info

Name	CENPN
Key Genes/Proteins	AND, APOPTOSIS, CREB, AUTOPHAGY, VAMP8
Related Diseases	Paclitaxel Resistance, Nasopharyngeal Carcinoma, Poor Prognosis, Apoptosis Resistance, Carcinoma
Related Pathways	CREB-VAMP8 Signaling Axis, Apoptosis, apoptosis pathway

Pathway Diagram

graph TD
    CENPN["CENPN"]
    CENPN -->|"inhibits"| Autophagy["Autophagy"]
    CENPN -->|"inhibits"| CREB_VAMP8_Signaling_Axis["CREB-VAMP8 Signaling Axis"]
    CENPN -->|"expressed in"| Nasopharyngeal_Carcinoma["Nasopharyngeal Carcinoma"]
    CENPN -->|"inhibits"| Carcinoma["Carcinoma"]
    CENPN -->|"activates"| Apoptosis["Apoptosis"]
    CENPN -->|"activates"| AND["AND"]
    CENPN -->|"activates"| APOPTOSIS["APOPTOSIS"]
    CENPN -->|"inhibits"| CREB["CREB"]
    APOPTOSIS -->|"activates"| CENPN
    AUTOPHAGY["AUTOPHAGY"] -->|"inhibits"| CENPN
    VAMP8["VAMP8"] -->|"inhibits"| CENPN

Outgoing (15)

Target	Relation	Type	Str
Autophagy	inhibits	process	0.95
Paclitaxel Resistance	associated_with	phenotype	0.95
CREB-VAMP8 Signaling Axis	inhibits	pathway	0.95
Nasopharyngeal Carcinoma	expressed_in	disease	0.90
Poor Prognosis	associated_with	phenotype	0.90
Cell Proliferation	associated_with	process	0.85
Apoptosis Resistance	associated_with	phenotype	0.85
Carcinoma	inhibits	disease	0.65
Apoptosis	activates	pathway	0.60
AND	activates	gene	0.60
APOPTOSIS	activates	gene	0.60
CREB	inhibits	gene	0.60
AUTOPHAGY	inhibits	gene	0.60
VAMP8	inhibits	gene	0.60
apoptosis pathway	participates_in	pathway	0.60

Incoming (3)

Source	Relation	Type	Str
APOPTOSIS	activates	gene	0.60
AUTOPHAGY	inhibits	gene	0.60
VAMP8	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity