protein

DCCPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DCCPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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Summary

Dcc Netrin 1 Receptor Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	DCCPROTEIN
Full Name	DCC Netrin 1 Receptor Protein
Protein Family	Ig superfamily, DCC family
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	</td><td>Plasma membrane, cytoplasm</td></tr>
Molecular Weight	~175 kDa
Amino Acids	447 aa
UniProt ID	Q9Y266
GeneCards	DCCPROTEIN
Human Protein Atlas	DCCPROTEIN
Transmembrane Domain	Single pass α-helical transmembrane region
Cytoplasmic Tail	Contains multiple signaling motifs:
With Netrin-1	Activates pro-survival signaling (PI3K/AKT, MAPK/ERK pathways)
Without Netrin-1	Induces apoptosis through caspase activation and mitochondrial pathways
Associated Diseases	Als, cancer
Interactions	AKT, APOPTOSIS, CANCER, CD44, EPHA4, FGF10
KG Connections	82 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: DCCPROTEIN — AlphaFold Q9Y266 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

DCC Netrin 1 Receptor Protein

protein · 1040 words

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Pathway Diagram

graph TD
    DCCPROTEIN["DCCPROTEIN"]
    neurodegeneration["neurodegeneration"]
    DCCPROTEIN -->|"implicated_in"| neurodegeneration
    style DCCPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DCCPROTEIN in their description or question text

No additional research found