gene

GMM

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GMM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

6Connections

0Hypotheses

0Analyses

4Outgoing

2Incoming

Summary

GMM Gene - GM2 Activator Protein

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🧬 Gene Info

Gene Symbol	GMM
Aliases	Page for GMM Gene
Chromosome	5q31.3
Function	The GM2 activator protein serves as a substrate-specific co-factor for the enzyme hexosaminidase A (Hex A).
Primary Expression	Brain, Liver, Kidney, Testis
UniProt ID	P17900
NCBI Gene ID	755
Ensembl ID	ENSG00000113595
OMIM	613512
GeneCards	GMM
Human Protein Atlas	GMM
Symbol [@molecular] GMM Full Name	GM2 Activator Protein
Interactions	IMMUNE INFILTRATION, HRAS, INFLAMMATION
KG Connections	6 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GMM — AlphaFold P17900 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

flowchart TD
    GMM(["GMM"])
    Ulcerative_Colitis["Ulcerative Colitis"]
    Inflammation["Inflammation"]
    MMP9(["MMP9"])
    IMMUNE_INFILTRATION(["IMMUNE INFILTRATION"])
    HRAS(["HRAS"])
    INFLAMMATION(["INFLAMMATION"])
    neurodegeneration["neurodegeneration"]

    GMM -->|"interacts with"| Ulcerative_Colitis
    GMM -->|"interacts with"| Inflammation
    GMM -->|"therapeutic target"| MMP9
    GMM -->|"interacts with"| IMMUNE_INFILTRATION
    HRAS -->|"interacts with"| GMM
    INFLAMMATION -->|"interacts with"| GMM
    GMM -->|"implicated in"| neurodegeneration

    style GMM fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (4)

Target	Relation	Type	Str
Ulcerative Colitis	interacts_with	disease	0.65
Inflammation	interacts_with	disease	0.65
MMP9	therapeutic_target	gene	0.60
IMMUNE INFILTRATION	interacts_with	gene	0.60

Incoming (2)

Source	Relation	Type	Str
HRAS	interacts_with	gene	0.60
INFLAMMATION	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

GMM