gene 523 words KG: GMM
Contents

GMM Gene - GM2 Activator Protein

🧬 Gene Info
Gene SymbolGMM
AliasesPage for GMM Gene
Chromosome5q31.3
FunctionThe GM2 activator protein serves as a substrate-specific co-factor for the enzyme hexosaminidase A (Hex A).
Primary ExpressionBrain, Liver, Kidney, Testis
UniProt IDP17900
NCBI Gene ID755
Ensembl IDENSG00000113595
OMIM613512
GeneCardsGMM
Human Protein AtlasGMM
InteractionsHRAS, IMMUNE INFILTRATION, INFLAMMATION
KG Connections6 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.77
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69
Ganglioside Rebalancing Therapy
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (7)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (3)

Neurodegeneration
disease · KG edge: implicated_in
HRAS (Harvey Rat Sarcoma Viral Oncogene Homolog)
gene · KG edge: interacts_with
MMP9 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (6 edges)

HRAS interacts_with GMM
GMM therapeutic_target MMP9
INFLAMMATION interacts_with GMM
GMM interacts_with IMMUNE INFILTRATION
GMM interacts_with Ulcerative Colitis
GMM interacts_with Inflammation

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