Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GLUCOCEREBROSIDASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
GLUCOCEREBROSIDASE["GLUCOCEREBROSIDASE"]
GLUCOCEREBROSIDASE -->|"degrades"| Glucocerebrosides["Glucocerebrosides"]
GLUCOCEREBROSIDASE -->|"catalyzes"| Sphingolipid_Metabolism["Sphingolipid Metabolism"]
GLUCOCEREBROSIDASE -->|"treats"| Gaucher_Disease["Gaucher Disease"]
GLUCOCEREBROSIDASE -->|"regulates"| Lipid_Metabolism["Lipid Metabolism"]
GLUCOCEREBROSIDASE -->|"regulates"| Lysosomal_Autophagy["Lysosomal Autophagy"]
GBA["GBA"] -->|"encodes"| GLUCOCEREBROSIDASE
GBA1["GBA1"] -->|"encodes"| GLUCOCEREBROSIDASE
Bi_Htfr1["Bi-Htfr1"] -->|"upregulates"| GLUCOCEREBROSIDASE| Target | Relation | Type | Str |
|---|---|---|---|
| Gaucher disease | associated_with | disease | 0.95 |
| Glucocerebrosides | degrades | compound | 0.95 |
| Parkinson's disease | associated_with | disease | 0.90 |
| glucocerebroside | degrades | compound | 0.90 |
| Sphingolipid Metabolism | regulates | pathway | 0.85 |
| Gaucher Disease | treats | disease | 0.85 |
| Glucocerebrosides | substrate_of | compound | 0.85 |
| Lipid Metabolism | regulates | pathway | 0.85 |
| Lysosomal Autophagy | regulates | process | 0.80 |
| glucosylceramide | regulates | process | 0.70 |
| lysosomal pathways | regulates | pathway | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity