Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Inflammatory gene expression: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Very Long Chain Ceramides | promotes | compound | 0.90 |
| SIRT1 | regulates | protein | 0.90 |
| HDAC2 | represses | gene | 0.90 |
| ceramides | upregulates | compound | 0.88 |
| Il10 Deficiency | promotes | phenotype | 0.85 |
| RIPK1 | upregulates | protein | 0.85 |
| NMDA receptor signaling | regulates | mechanism | 0.80 |
| RIPK1 | upregulates | gene | 0.80 |
| APOE4 astrocytes | activates | cell_type | 0.70 |
| ARNTL | regulates | gene | 0.70 |
| CLOCK | regulates | gene | 0.70 |
| HDAC2 | associated_with | gene | 0.70 |
| circadian clock | regulates | phenotype | 0.70 |
| HDAC2 | inhibits | gene | 0.70 |
| NF-κB | activates | protein | 0.70 |
| SPI1 | regulates | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
immunology | 2026-04-15 | 0 hypotheses
neurodegeneration | 2026-04-10 | 0 hypotheses
neuroinflammation | 2026-04-08 | 7 hypotheses Top: 0.455
immunology | 2026-04-08 | 8 hypotheses Top: 0.380
chronobiology | 2026-04-08 | 7 hypotheses Top: 0.455
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.57 · 2026-04-28
closed · Rounds: 4 · Score: 0.12 · 2026-04-27
closed · Rounds: 4 · Score: 0.42 · 2026-04-27
closed · Rounds: 4 · Score: 0.48 · 2026-04-27
closed · Rounds: 4 · Score: 0.47 · 2026-04-27
closed · Rounds: 4 · Score: 0.52 · 2026-04-27
closed · Rounds: 4 · Score: 0.72 · 2026-04-27
closed · Rounds: 0 · Score: 0.50 · 2026-04-21
closed · Rounds: 0 · Score: 0.56 · 2026-04-21
closed · Rounds: 4 · Score: 0.80 · 2026-04-16
Hypotheses and analyses mentioning Inflammatory gene expression in their description or question text
No additional research found