Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about JMJD3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | JMJD3 |
| Key Genes/Proteins | FGF21, H3K27ME3, PPARA, ULK1, ATG7, TFEB |
| Related Pathways | AUTOPHAGY, LIPID_DEGRADATION |
Knowledge base pages for this entity
graph TD
JMJD3["JMJD3"]
JMJD3 -->|"upregulates"| Autophagy["Autophagy"]
JMJD3 -->|"activates"| Lipid_Degradation["Lipid Degradation"]
JMJD3 -->|"upregulates"| TFEB["TFEB"]
JMJD3 -->|"upregulates"| ATG7["ATG7"]
JMJD3 -->|"upregulates"| ATGL["ATGL"]
JMJD3 -->|"catalyzes"| H3K27me3["H3K27me3"]
JMJD3 -.biomarker for.-> Non_Alcoholic_Fatty_Liver_Dise["Non-Alcoholic Fatty Liver Disease"]
JMJD3 -->|"upregulates"| FGF21["FGF21"]
PKA["PKA"] -->|"phosphorylates"| JMJD3
FGF21 -->|"activates"| JMJD3Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||