KDM4A

Understanding Entity Pages

This page aggregates everything SciDEX knows about KDM4A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

KDM4A gene encoding JMJD2A - a Jumonji C domain histone demethylase involved in epigenetic regulation and implicated in neurodegeneration

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graph TD
    KDM4A["<b>KDM4A</b>"]
    Als{"Als"}
    KDM4A -->|"associated with"| Als
    Cancer{"Cancer"}
    KDM4A -->|"associated with"| Cancer
    FGFR3["FGFR3"]
    KDM4A -->|"associated with"| FGFR3
    TP53["TP53"]
    KDM4A -->|"associated with"| TP53
    KRAS["KRAS"]
    KDM4A -->|"associated with"| KRAS
    BICD2["BICD2"]
    KDM4A -->|"associated with"| BICD2
    MITF["MITF"]
    KDM4A -->|"associated with"| MITF
    CANCER["CANCER"]
    KDM4A -->|"associated with"| CANCER
    HSPA1A["HSPA1A"]
    KDM4A -->|"associated with"| HSPA1A
    BRCA2["BRCA2"]
    KDM4A -->|"associated with"| BRCA2
    neurodegeneration["neurodegeneration"]
    KDM4A -->|"implicated in"| neurodegeneration
    IDH1["IDH1"]
    IDH1 -->|"upregulates"| KDM4A
    style KDM4A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0