Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MYASTHENIA GRAVIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
MYASTHENIA_GRAVIS["MYASTHENIA GRAVIS"]
MYASTHENIA_GRAVIS -->|"inhibits"| Blood_Brain_Barrier["Blood-Brain Barrier"]
MYASTHENIA_GRAVIS -->|"inhibits"| Lysosomal_Degradation["Lysosomal Degradation"]
MYASTHENIA_GRAVIS -->|"inhibits"| Complement["Complement"]
autoantibodies["autoantibodies"] -->|"causes"| MYASTHENIA_GRAVIS
plasma_cells["plasma cells"] -->|"promotes"| MYASTHENIA_GRAVIS
IVIg["IVIg"] -->|"treats"| MYASTHENIA_GRAVIS
AND["AND"] -->|"regulates"| MYASTHENIA_GRAVIS
COMPLEMENT["COMPLEMENT"] -->|"inhibits"| MYASTHENIA_GRAVIS
NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"] -.biomarker for.-> MYASTHENIA_GRAVIS
NR3C1["NR3C1"] -->|"interacts"| MYASTHENIA_GRAVIS| Target | Relation | Type | Str |
|---|---|---|---|
| Blood-Brain Barrier | inhibits | pathway | 0.55 |
| Lysosomal Degradation | inhibits | pathway | 0.55 |
| Complement | inhibits | pathway | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| autoantibodies | causes | protein | 0.90 |
| plasma cells | promotes | cell_type | 0.85 |
| Ivig | treats | drug | 0.85 |
| FCGRT | associated_with | entity | 0.85 |
| IVIg | treats | drug | 0.80 |
| AND | expressed_in | gene | 0.65 |
| KRAS | associated_with | gene | 0.65 |
| PARKINSON | associated_with | gene | 0.65 |
| ALZHEIMER | associated_with | gene | 0.65 |
| ALZHEIMER'S DISEASE | associated_with | gene | 0.65 |
| NEURODEGENERATIVE DISEASES | biomarker_for | gene | 0.65 |
| PARKINSON'S DISEASE | associated_with | gene | 0.65 |
| AND | regulates | gene | 0.65 |
| COMPLEMENT | inhibits | gene | 0.65 |
| FCGRT | associated_with | gene | 0.65 |
| AND | associated_with | gene | 0.65 |
| HSPG2 | associated_with | gene | 0.65 |
| CANCER | interacts_with | gene | 0.65 |
| GENES | interacts_with | gene | 0.65 |
| NR3C1 | interacts_with | gene | 0.65 |
| FCGRT | biomarker_for | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity