Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NDUFV1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | NDUFV1 |
| Full Name | NADH:Ubiquinone Oxidoreductase Core Subunit V1 |
| Chromosome | 11q13.2 |
| Protein Type | Oxidoreductase |
| Function | encodes a core subunit of mitochondrial complex I (NADH:ubiquinone oxidoreductase). |
| Primary Expression | brain tissue: |
| UniProt ID | [P22415](https://www.uniprot.org/uniprot/P22415) |
| Ensembl ID | ENSG00000167792 |
| GeneCards | NDUFV1 |
| Human Protein Atlas | NDUFV1 |
| Associated Diseases | neurodegeneration |
| Interactions | GABRB2, GABRB3 |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
NDUFV1["<b>NDUFV1</b>"]
Als{"Als"}
NDUFV1 -->|"therapeutic target"| Als
MAPK14["MAPK14"]
NDUFV1 -->|"therapeutic target"| MAPK14
PLEC["PLEC"]
NDUFV1 -->|"therapeutic target"| PLEC
CRYAB["CRYAB"]
NDUFV1 -->|"therapeutic target"| CRYAB
CASP3["CASP3"]
NDUFV1 -->|"therapeutic target"| CASP3
Mapk(["Mapk"])
NDUFV1 -->|"therapeutic target"| Mapk
neurodegeneration["neurodegeneration"]
NDUFV1 -->|"implicated in"| neurodegeneration
GFAP["GFAP"]
GFAP -->|"therapeutic target"| NDUFV1
style NDUFV1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| Als | therapeutic_target | disease | 0.65 |
| MAPK14 | therapeutic_target | gene | 0.60 |
| PLEC | therapeutic_target | gene | 0.60 |
| CRYAB | therapeutic_target | gene | 0.60 |
| CASP3 | therapeutic_target | gene | 0.60 |
| Mapk | therapeutic_target | pathway | 0.60 |
| benchmark_ot_ad_answer_key:NDUFV1 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
| GFAP | therapeutic_target | gene | 0.60 |
| GABRB2 | phosphorylates | gene | 0.60 |
| GABRB3 | phosphorylates | gene | 0.60 |
| benchmark_ot_ad_answer_key:NDUFV1 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||