MAPK14

Understanding Entity Pages

This page aggregates everything SciDEX knows about MAPK14: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

MAPK14 is a gene implicated in neurodegeneration research. Key relationships include: interacts with, therapeutic target, activates. Associated with ALS, Aging, Als. Connected to 306 entities in the SciDEX knowledge graph.

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graph TD
    MAPK14["MAPK14"] -->|"Inhibits"| TTP["TTP"]
    MAPK14["MAPK14"] -->|"Interacts With"| Cancer["Cancer"]
    MAPK14["MAPK14"] -->|"Interacts With"| Als["Als"]
    MAPK14["MAPK14"] -->|"Interacts With"| Ms["Ms"]
    MAPK14["MAPK14"] -->|"Interacts With"| Fibrosis["Fibrosis"]
    MAPK14["MAPK14"] -->|"Therapeutic Target"| Osteoporosis["Osteoporosis"]
    MAPK14["MAPK14"] -->|"Interacts With"| BECN1["BECN1"]
    MAPK14["MAPK14"] -->|"Interacts With"| ATF6["ATF6"]
    OPTN["OPTN"] -->|"Interacts With"| MAPK14["MAPK14"]
    CASP3["CASP3"] -->|"Interacts With"| MAPK14["MAPK14"]
    AKT1["AKT1"] -->|"Interacts With"| MAPK14["MAPK14"]
    CALCOCO2["CALCOCO2"] -->|"Interacts With"| MAPK14["MAPK14"]
    CGAS["CGAS"] -->|"Interacts With"| MAPK14["MAPK14"]
    style MAPK14 fill:#8d4900,color:#e0e0e0
    style TTP fill:#0d47a1,color:#e0e0e0
    style Cancer fill:#b71c1c,color:#e0e0e0
    style Als fill:#b71c1c,color:#e0e0e0
    style Ms fill:#b71c1c,color:#e0e0e0
    style Fibrosis fill:#b71c1c,color:#e0e0e0
    style Osteoporosis fill:#b71c1c,color:#e0e0e0
    style BECN1 fill:#8d4900,color:#e0e0e0
    style ATF6 fill:#8d4900,color:#e0e0e0
    style OPTN fill:#8d4900,color:#e0e0e0
    style CASP3 fill:#8d4900,color:#e0e0e0
    style AKT1 fill:#8d4900,color:#e0e0e0
    style CALCOCO2 fill:#8d4900,color:#e0e0e0
    style CGAS fill:#8d4900,color:#e0e0e0