Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEFLPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | NEFLPROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | | Neuronal axon (cytoskeleton) |- \! Protein Family | Type IV intermediate filam |
| Amino Acids | 543 aa |
| GeneCards | NEFLPROTEIN |
| Human Protein Atlas | NEFLPROTEIN |
| Associated Diseases | Alzheimers_disease |
| Interactions | ALS, AMYOTROPHIC LATERAL SCLEROSIS, BCL2, BNIP3L, C9ORF72, CNR1 |
| SciDEX Hypotheses | Plasma NfL Elevation Secondary to BBB-Associated T Plasma NfL Elevation Secondary to BBB-Associated T |
| KG Connections | 197 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
NEFLPROTEIN["NEFLPROTEIN"]
neurodegeneration["neurodegeneration"]
NEFLPROTEIN -->|"implicated_in"| neurodegeneration
style NEFLPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NEFLPROTEIN in their description or question text
No additional research found