Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEUROTROPHINS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEUROTROPHINS |
| Key Genes/Proteins | NGF, TRK_RECEPTORS, P75NTR |
| Related Diseases | NEURONAL_SURVIVAL, Huntington's Disease, Peripheral Neuropathy, SYNAPTIC_PLASTICITY |
Knowledge base pages for this entity
graph TD
NEUROTROPHINS["NEUROTROPHINS"]
NEUROTROPHINS -->|"regulates"| Neuronal_Survival["Neuronal Survival"]
NEUROTROPHINS -->|"binds"| P75NTR["P75NTR"]
NEUROTROPHINS -->|"binds"| TRK["TRK"]
NEUROTROPHINS -->|"regulates"| Nervous_System_Development["Nervous System Development"]
NEUROTROPHINS -->|"regulates"| Nervous_System_Maintenance["Nervous System Maintenance"]
NEUROTROPHINS -->|"modulates"| Synaptic_Function["Synaptic Function"]
NEUROTROPHINS -->|"activates"| NEURONAL_SURVIVAL["NEURONAL_SURVIVAL"]
NEUROTROPHINS -->|"treats"| Huntington_s_Disease["Huntington's Disease"]
NGF["NGF"] -->|"component_of"| NEUROTROPHINS
TRK_RECEPTORS["TRK_RECEPTORS"] -->|"interacts"| NEUROTROPHINS
P75NTR -->|"interacts"| NEUROTROPHINS| Target | Relation | Type | Str |
|---|---|---|---|
| Neuronal Survival | regulates | process | 0.95 |
| TRK | binds | receptor | 0.95 |
| Nervous System Development | regulates | process | 0.95 |
| Nervous System Maintenance | regulates | process | 0.95 |
| Neurodegeneration | associated_with | process | 0.95 |
| Synaptic Function | modulates | process | 0.90 |
| Synaptic Plasticity | associated_with | process | 0.90 |
| NEURONAL_SURVIVAL | activates | phenotype | 0.72 |
| Huntington's Disease | treats | disease | 0.65 |
| Peripheral Neuropathy | treats | disease | 0.65 |
| SYNAPTIC_PLASTICITY | regulates | phenotype | 0.64 |
| NERVOUS_SYSTEM | regulates | brain_region | 0.64 |
| ALS | treats | disease | 0.56 |
| AD | treats | disease | 0.56 |
| PD | treats | disease | 0.56 |
| Source | Relation | Type | Str |
|---|---|---|---|
| NGF | component_of | protein | 0.95 |
| TRK_RECEPTORS | interacts_with | protein | 0.72 |
| P75NTR | interacts_with | protein | 0.72 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||