Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about P-TAU217: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | P-TAU217 |
| Related Diseases | Alzheimer's disease |
Knowledge base pages for this entity
graph TD
P_TAU217["P-TAU217"]
P_TAU217 -->|"correlates_with"| neurodegeneration["neurodegeneration"]
P_TAU217 -.biomarker for.-> A__pathology["Abeta pathology"]
P_TAU217 -->|"correlates_with"| Brain_Atrophy["Brain Atrophy"]
P_TAU217 -->|"correlates_with"| Cognitive_Impairment["Cognitive Impairment"]
P_TAU217 -.biomarker for.-> Neurodegeneration["Neurodegeneration"]
P_TAU217 -.biomarker for.-> Alzheimer_Disease["Alzheimer Disease"]
P_TAU217 -.biomarker for.-> Alzheimer_s_Disease["Alzheimer's Disease"]
P_TAU217 -.biomarker for.-> amyloid_beta_pathology["amyloid-beta pathology"]
mAb2A7["mAb2A7"] -->|"targets"| P_TAU217
Mab2A7["Mab2A7"] -->|"targets"| P_TAU217
Tau_Positivity["Tau Positivity"] -->|"correlates_with"| P_TAU217
Amyloid_Beta_Positivity["Amyloid Beta Positivity"] -->|"correlates_with"| P_TAU217
APOE["APOE"] -->|"modulates"| P_TAU217| Target | Relation | Type | Str |
|---|---|---|---|
| neurodegeneration | correlates_with | process | 1.00 |
| Alzheimer's disease | biomarker_for | disease | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| mAb2A7 | targets | drug | 0.98 |
| Mab2A7 | targets | drug | 0.95 |
| Tau Positivity | correlates_with | phenotype | 0.92 |
| Amyloid Beta Positivity | correlates_with | phenotype | 0.90 |
| obicetrapib | suppresses | drug | 0.88 |
| Cardiovascular Risk | modulates | phenotype | 0.85 |
| APOE | modulates | gene | 0.75 |
| mAb2A7 | inhibits | drug | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||