protein

PFKL

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PFKL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

18Connections

0Hypotheses

0Analyses

12Outgoing

6Incoming

Summary

Page for PFKL Protein

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🔬 Protein Info

Gene Symbol	PFKL
Function	PFKL Protein is a protein involved in various cellular processes.
Molecular Weight	780 kDa
Pathways	Glycolysis, lipid metabolism, LIPID METABOLISM, GLYCOLYSIS
GeneCards	PFKL
Human Protein Atlas	PFKL
Associated Diseases	Tumor Cell Proliferation
Interactions	PLIN2, CPT1A
KG Connections	18 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (3)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    PFKL["<b>PFKL</b>"]
    Lipid_Droplet_Mitochondria_Tet["Lipid Droplet-Mitochondria Tethering"]
    PFKL -->|"associated_with"| Lipid_Droplet_Mitochondria_Tet
    Lipolysis["Lipolysis"]
    PFKL -->|"regulates"| Lipolysis
    PLIN2["PLIN2"]
    PFKL -->|"phosphorylates"| PLIN2
    LIPID_DROPLET_MITOCHONDRIA_TET["LIPID DROPLET-MITOCHONDRIA TETHERING"]
    PFKL -->|"associated_with"| LIPID_DROPLET_MITOCHONDRIA_TET
    Lipid_Droplet["Lipid Droplet"]
    PFKL -->|"associated_with"| Lipid_Droplet
    Mitochondria["Mitochondria"]
    PFKL -->|"associated_with"| Mitochondria
    GLUCOSE_DEPRIVATION["GLUCOSE DEPRIVATION"]
    GLUCOSE_DEPRIVATION -->|"phosphorylates"| PFKL
    Glucose_Deprivation["Glucose Deprivation"]
    Glucose_Deprivation -->|"phosphorylates"| PFKL
    style PFKL fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#4fc3f7

Outgoing (12)

Target	Relation	Type	Str
PLIN2	phosphorylates	entity	0.95
LIPID DROPLET-MITOCHONDRIA TETHERING	associated_with	entity	0.95
PLIN2	interacts_with	entity	0.90
TUMOR CELL PROLIFERATION	associated_with	entity	0.90
tumor cell proliferation	drives	phenotype	0.85
tumor cell proliferation	promotes	process	0.80
PLIN2	activates	gene	0.60
lipid metabolism	participates_in	pathway	0.60
TUMOR	activates	disease	0.50
CELL PROLIFERATION	activates	concept	0.50
LIPID METABOLISM	regulates	pathway	0.50
GLYCOLYSIS	regulates	pathway	0.50

Incoming (6)

Source	Relation	Type	Str
GLUCOSE DEPRIVATION	phosphorylates	entity	0.90
glucose deprivation	causes	process	0.85
CPT1A	activates	gene	0.60
MITOCHONDRIA	activates	cell_type	0.50
PLIN2	activates	gene	0.50
MITOCHONDRIA	regulates	cell_type	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found