Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PRRG4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | PRRG4 |
| Pathways | oxidative stress response |
| GeneCards | PRRG4 |
| Human Protein Atlas | PRRG4 |
| Associated Diseases | autism spectrum disorder |
| Interactions | RHOA, MAGI2, GENES, AND |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PRRG4["PRRG4"] -->|"contributes to"| Autism["Autism"]
style Autism fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
PRRG4["PRRG4"] -->|"contributes to"| Tumor["Tumor"]
style Tumor fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
PRRG4["PRRG4"] -->|"implicated in"| autism_spectrum_disorder["autism spectrum disorder"]
style autism_spectrum_disorder fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
PRRG4["PRRG4"] -->|"activates"| RHOA["RHOA"]
style RHOA fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
PRRG4["PRRG4"] -->|"contributes to"| GLA["GLA"]
style GLA fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
PRRG4["PRRG4"] -->|"activates"| MAGI2["MAGI2"]
style MAGI2 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
PRRG4["PRRG4"] -->|"participates in"| oxidative_stress_response["oxidative stress response"]
style oxidative_stress_response fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
RHOA_1["RHOA"] -->|"activates"| PRRG4["PRRG4"]
style RHOA_1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
GLA_2["GLA"] -->|"contributes to"| PRRG4["PRRG4"]
style GLA_2 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
MAGI2_3["MAGI2"] -->|"activates"| PRRG4["PRRG4"]
style MAGI2_3 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
GENES["GENES"] -->|"activates"| PRRG4["PRRG4"]
style GENES fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
AND["AND"] -->|"activates"| PRRG4["PRRG4"]
style AND fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
style PRRG4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold| Target | Relation | Type | Str |
|---|---|---|---|
| Autism | contributes_to | disease | 0.65 |
| Tumor | contributes_to | disease | 0.65 |
| autism spectrum disorder | implicated_in | disease | 0.60 |
| RHOA | activates | gene | 0.60 |
| GLA | contributes_to | gene | 0.60 |
| MAGI2 | activates | gene | 0.60 |
| autism spectrum disorder | activates | disease | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| autism spectrum disorder | interacts_with | disease | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||