Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RBM10PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
RBM10 (RNA Binding Motif Protein 10) is a nuclear RNA binding protein that plays critical roles in alternative splicing, gene expression regulation, and neuronal cell survival.
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| Gene Symbol | RBM10PROTEIN |
| Full Name | RBM10 |
| Protein Family | RRM (RNA Recognition Motif) family |
| Function | is a nuclear RNA binding protein that plays critical roles in alternative splicing, gene expression regulation, and neuronal cell survival. |
| Molecular Weight | ~94 kDa |
| Amino Acids | 90 aa |
| UniProt ID | P98175 |
| GeneCards | RBM10PROTEIN |
| Human Protein Atlas | RBM10PROTEIN |
| SMN2 | Regulation of exon 7 inclusion, affecting motor neuron survival |
| Caspase-2 pre-mRNA | Alternative splicing regulates apoptotic pathways in neurons [@jackson2015] |
| Neat1 lncRNA | Regulation of nuclear paraspeckle formation and gene expression [@con2022] |
| Associated Diseases | Leukemia, Multiple Sclerosis, Neurodegeneration |
| Interactions | APOPTOSIS, BCL2, BCL2A1, CANCER, XIAP |
| KG Connections | 16 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
RBM10PROTEIN["RBM10PROTEIN"]
neurodegeneration["neurodegeneration"]
RBM10PROTEIN -->|"implicated_in"| neurodegeneration
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RBM10PROTEIN in their description or question text
No additional research found