Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RNA processing: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Amyotrophic Lateral Sclerosis | involved_in | disease | 0.80 |
| ALS | involved_in | disease | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| TDP-43 | involved_in | protein | 0.90 |
| TARDBP | regulates | protein | 0.90 |
| SNCA | interacts_with | protein | 0.85 |
| Tdp-43 | regulates | protein | 0.85 |
| HNRNP | involved_in | protein | 0.85 |
| HUNTINGTIN | regulates | protein | 0.80 |
| SETX | regulates | protein | 0.80 |
| Setx Depletion | modulates | mechanism | 0.80 |
| ALZHEIMER'S DISEASE | associated_with | disease | 0.75 |
| Stress Granules | associated_with | cell_type | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| RBM45 Liquid-Liquid Phase Separation Dominance Hijacks RNA P | 0.868 | als | - |
| MATR3 Nuclear Body Disruption Impairs RNA Processing Hubs an | 0.801 | als | - |
| FUS Phase Separation Dominance in FTD-TDP: Aberrant Condensa | 0.683 | frontotemporal-dementia | - |
| Mitochondrial RNA Processing Enhancement | 0.000 | - | RNA binding protein dysregulation across |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-01 | 13 hypotheses Top: 0.720
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.72 · 2026-04-12
closed · Rounds: 4 · Score: 0.88 · 2026-04-06
Hypotheses and analyses mentioning RNA processing in their description or question text
No additional research found