gene

RPL4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPL4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

9Connections
0Hypotheses
0Analyses
1Outgoing
8Incoming

Summary

Gene profile: RPL4

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🧬 Gene Info
Gene SymbolRPL4
Full NameRibosomal Protein L4
Chromosome15q22.1
Functionencodes a ribosomal protein that is a component of the 60S large ribosomal subunit.
Molecular Weight~47 kDa
Amino Acids397 aa
Exons9
UniProt IDP36551
NCBI Gene ID6123
GeneCardsRPL4
Human Protein AtlasRPL4
Protein Length397 amino acids
Associated Diseasesneurodegeneration
InteractionsRas, ATP
KG Connections9 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: RPL4 — AlphaFold P36551 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (11)

Knowledge base pages for this entity

Canonical Page

RPL4 — Ribosomal Protein L4

gene · 1767 words

RPL32 Gene - Ribosomal Protein L32

gene · 2739 words

RPL28 — Ribosomal Protein L28

gene · 1702 words

rpl21

gene · 1502 words

PPP1R7 — SDS22 (Protein Phosphatase 1 Regulatory Subunit 7)

gene · 1336 words

COX15 Protein

protein · 1289 words

Pathway Diagram

flowchart TD
    N0["RPL4"]
    N1["Ras"]
    N0 -->|"activates"| N1
    N2["PPP1R7"]
    N2 -->|"associated with"| N0
    N3["ABCB1"]
    N3 -->|"associated with"| N0
    N4["PEX3"]
    N4 -->|"associated with"| N0
    N5["VPS33A"]
    N5 -->|"associated with"| N0
    N6["VPS16"]
    N6 -->|"associated with"| N0
    N7["COX15"]
    N7 -->|"associated with"| N0
    N8["ATP"]
    N8 -->|"activates"| N0
    N9["ACSL5"]
    N9 -->|"associated with"| N0
    N10["neurodegeneration"]
    N0 -->|"implicated in"| N10

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 protein
    class N2 gene
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene
    class N9 gene

Outgoing (1)

TargetRelationTypeStr
Rasactivatesprotein0.60

Incoming (8)

SourceRelationTypeStr
PPP1R7associated_withgene0.60
ABCB1associated_withgene0.60
PEX3associated_withgene0.60
VPS33Aassociated_withgene0.60
VPS16associated_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found