Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPL4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | RPL4 |
| Full Name | Ribosomal Protein L4 |
| Chromosome | 15q22.1 |
| Function | encodes a ribosomal protein that is a component of the 60S large ribosomal subunit. |
| Molecular Weight | ~47 kDa |
| Amino Acids | 397 aa |
| Exons | 9 |
| UniProt ID | P36551 |
| NCBI Gene ID | 6123 |
| GeneCards | RPL4 |
| Human Protein Atlas | RPL4 |
| Protein Length | 397 amino acids |
| Associated Diseases | neurodegeneration |
| Interactions | Ras, ATP |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["RPL4"]
N1["Ras"]
N0 -->|"activates"| N1
N2["PPP1R7"]
N2 -->|"associated with"| N0
N3["ABCB1"]
N3 -->|"associated with"| N0
N4["PEX3"]
N4 -->|"associated with"| N0
N5["VPS33A"]
N5 -->|"associated with"| N0
N6["VPS16"]
N6 -->|"associated with"| N0
N7["COX15"]
N7 -->|"associated with"| N0
N8["ATP"]
N8 -->|"activates"| N0
N9["ACSL5"]
N9 -->|"associated with"| N0
N10["neurodegeneration"]
N0 -->|"implicated in"| N10
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 protein
class N2 gene
class N3 gene
class N4 gene
class N5 gene
class N6 gene
class N7 gene
class N8 gene
class N9 gene| Target | Relation | Type | Str |
|---|---|---|---|
| Ras | activates | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||