gene 1,767 words KG: RPL4 2026-03-25
kind:genesection:genesstate:published
Contents

RPL4 — Ribosomal Protein L4

🧬 Gene Info
Gene SymbolRPL4
Full NameRibosomal Protein L4
Chromosome15q22.1
Functionencodes a ribosomal protein that is a component of the 60S large ribosomal subunit.
Molecular Weight~47 kDa
Amino Acids397 aa
Exons9
UniProt IDP36551
NCBI Gene ID6123
GeneCardsRPL4
Human Protein AtlasRPL4
Protein Length397 amino acids
Associated Diseasesneurodegeneration
InteractionsRas, ATP
KG Connections9 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (9)

APOE-Dependent Autophagy Restoration
Score: 0.61
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.59
Phase-Separated Organelle Targeting
Score: 0.52
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Stress Granule Phase Separation Modulators
Score: 0.49

Related Analyses (5)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (9)

Ras-MAPK Signaling Pathway in Neurodegeneration
mechanism · KG edge: activates
VPS33A Gene
gene · KG edge: associated_with
VPS16 Gene
gene · KG edge: associated_with
PPP1R7 — SDS22 (Protein Phosphatase 1 Regulatory Subuni
gene · KG edge: associated_with
PEX3 Gene - Peroxisome Biogenesis Factor 3
gene · KG edge: associated_with

Knowledge Graph (9 edges)

RPL4 activates Ras
PPP1R7 associated_with RPL4
ABCB1 associated_with RPL4
PEX3 associated_with RPL4
VPS33A associated_with RPL4
VPS16 associated_with RPL4
COX15 associated_with RPL4
ATP activates RPL4
ACSL5 associated_with RPL4