Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SBFI26: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SBFI26 |
| Key Genes/Proteins | FABP5, HMOX1, ALOX12, SAT1, ALOX5, NFE2L2 |
| Related Diseases | Triple-Negative Breast Cancer |
| Related Pathways | Lipid peroxidation |
graph TD
SBFI26["SBFI26"]
SBFI26 -->|"treats"| Triple_Negative_Breast_Cancer["Triple-Negative Breast Cancer"]
SBFI26 -->|"inhibits"| FABP5["FABP5"]
SBFI26 -->|"inhibits"| MDA_MB_231["MDA-MB-231"]
SBFI26 -->|"downregulates"| Glutathione["Glutathione"]
SBFI26 -->|"upregulates"| HMOX1["HMOX1"]
SBFI26 -->|"upregulates"| ALOX12["ALOX12"]
SBFI26 -->|"upregulates"| SAT1["SAT1"]| Target | Relation | Type | Str |
|---|---|---|---|
| Ferroptosis | associated_with | process | 0.95 |
| Triple-Negative Breast Cancer | treats | disease | 0.90 |
| FABP5 | inhibits | protein | 0.90 |
| FABP5 | targets | protein | 0.90 |
| MDA-MB-231 | inhibits | cell_type | 0.90 |
| Glutathione | downregulates | compound | 0.88 |
| HMOX1 | upregulates | gene | 0.85 |
| ALOX12 | upregulates | gene | 0.85 |
| Glutathione | associated_with | compound | 0.85 |
| SAT1 | upregulates | gene | 0.85 |
| ALOX5 | upregulates | gene | 0.85 |
| NFE2L2 | downregulates | gene | 0.80 |
| Lipid peroxidation | associated_with | biological_process | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| MDA-MB-231 | associated_with | cell_type | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||