Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SAT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SAT1 |
| Key Genes/Proteins | FER, ALOX15, RNA, AND, NFE2L2, GENES |
| Related Diseases | DLBCL, Cancer, Ferroptosis, Lymphoma |
| Related Pathways | Ferroptosis |
Knowledge base pages for this entity
graph TD
SAT1["SAT1"]
SAT1 -->|"activates"| Cancer["Cancer"]
SAT1 -->|"activates"| FER["FER"]
SAT1 -->|"activates"| ALOX15["ALOX15"]
SAT1 -->|"activates"| RNA["RNA"]
SAT1 -->|"activates"| AND["AND"]
SAT1 -->|"activates"| NFE2L2["NFE2L2"]
SAT1 -->|"activates"| GENES["GENES"]
SAT1 -->|"activates"| Ferroptosis["Ferroptosis"]
SBFI26["SBFI26"] -->|"upregulates"| SAT1
CANCER["CANCER"] -->|"activates"| SAT1
HMOX1["HMOX1"] -->|"activates"| SAT1
GSH["GSH"] -->|"activates"| SAT1
CHAC1["CHAC1"] -->|"activates"| SAT1
ALOXE3["ALOXE3"] -->|"activates"| SAT1
ALOX12["ALOX12"] -->|"activates"| SAT1
ALOX5["ALOX5"] -->|"activates"| SAT1| Target | Relation | Type | Str |
|---|---|---|---|
| DLBCL | biomarker_for | disease | 0.80 |
| ferroptosis | promotes | process | 0.80 |
| Cancer | activates | disease | 0.65 |
| Ferroptosis | associated_with | disease | 0.65 |
| Lymphoma | associated_with | disease | 0.65 |
| FER | activates | gene | 0.60 |
| ALOX15 | activates | gene | 0.60 |
| RNA | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| NFE2L2 | activates | gene | 0.60 |
| GENES | activates | gene | 0.60 |
| Ferroptosis | activates | pathway | 0.60 |
| ALOX12 | activates | gene | 0.60 |
| ALOX5 | activates | gene | 0.60 |
| FERROPTOSIS | activates | gene | 0.60 |
| HMOX1 | activates | gene | 0.60 |
| CHAC1 | activates | gene | 0.60 |
| ALOXE3 | activates | gene | 0.60 |
| GSH | activates | gene | 0.60 |
| ATM | biomarker_for | gene | 0.60 |
| MTOR | biomarker_for | gene | 0.60 |
| FERROPTOSIS | associated_with | gene | 0.60 |
| RNA | associated_with | gene | 0.60 |
| BRD4 | biomarker_for | gene | 0.60 |
| Oxidative Phosphorylation | associated_with | pathway | 0.60 |
| Mtor | biomarker_for | pathway | 0.60 |
| Immune Response | associated_with | pathway | 0.60 |
| Cell Cycle | associated_with | pathway | 0.60 |
| Ras | activates | protein | 0.60 |
| SRXN1 | biomarker_for | gene | 0.60 |
| Fus | associated_with | protein | 0.60 |
| App | associated_with | protein | 0.60 |
| MTOR | therapeutic_target | gene | 0.60 |
| YBX1 | regulates | gene | 0.60 |
| JUN | activates | gene | 0.60 |
| HERC5 | regulates | gene | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| Ras | associated_with | protein | 0.60 |
| App | activates | protein | 0.60 |
| ferroptosis | participates_in | pathway | 0.60 |
| ferroptosis | activates | process | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| SBFI26 | upregulates | drug | 0.85 |
| CANCER | activates | gene | 0.60 |
| HMOX1 | activates | gene | 0.60 |
| GSH | activates | gene | 0.60 |
| CHAC1 | activates | gene | 0.60 |
| ALOXE3 | activates | gene | 0.60 |
| ALOX12 | activates | gene | 0.60 |
| ALOX5 | activates | gene | 0.60 |
| FERROPTOSIS | activates | gene | 0.60 |
| SRXN1 | biomarker_for | gene | 0.60 |
| ALOX15 | activates | gene | 0.60 |
| NFE2L2 | activates | gene | 0.60 |
| ATM | biomarker_for | gene | 0.60 |
| BRD4 | biomarker_for | gene | 0.60 |
| MTOR | biomarker_for | gene | 0.60 |
| PRDX1 | biomarker_for | gene | 0.60 |
| ACO1 | biomarker_for | gene | 0.60 |
| LPIN1 | biomarker_for | gene | 0.60 |
| MT1G | biomarker_for | gene | 0.60 |
| PEBP1 | biomarker_for | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||