gene

SNPH

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SNPH: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

10Connections

0Hypotheses

0Analyses

7Outgoing

3Incoming

Summary

SNPH is a gene implicated in neurodegeneration research. Key relationships include: expressed in, implicated in. Associated with Als, Alzheimer, Ms. Connected to 11 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	SNPH
Full Name	Synaphin
Chromosome	9p13.3
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	the brain and is localized to synaptic terminals[@beller2006]
Subcellular Localization	synaptic terminals[@beller2006]. SNPH has gained attention for its involvement in neurodegenerative diseases, particular
Molecular Weight	17 kDa
Amino Acids	149 aa
Exons	3
UniProt ID	[Q9Y4X5](https://www.uniprot.org/uniprot/Q9Y4X5)
Ensembl ID	ENSG00000168952
OMIM	611390
GeneCards	SNPH
Human Protein Atlas	SNPH
Synapsins	Member of the synapsin family of synaptic vesicle-associated phosphoproteins
Associated Diseases	neurodegeneration
KG Connections	10 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    SNPH["<b>SNPH</b>"]
    Alzheimer{"Alzheimer"}
    SNPH -->|"expressed in"| Alzheimer
    Ms{"Ms"}
    SNPH -->|"expressed in"| Ms
    Als{"Als"}
    SNPH -->|"expressed in"| Als
    MIRO1["MIRO1"]
    SNPH -->|"expressed in"| MIRO1
    Mitophagy(["Mitophagy"])
    SNPH -->|"expressed in"| Mitophagy
    APP["APP"]
    SNPH -->|"expressed in"| APP
    PRESENILIN["PRESENILIN"]
    SNPH -->|"expressed in"| PRESENILIN
    neurodegeneration["neurodegeneration"]
    SNPH -->|"implicated in"| neurodegeneration
    APP -->|"expressed in"| SNPH
    MITOPHAGY["MITOPHAGY"]
    MITOPHAGY -->|"expressed in"| SNPH
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"expressed in"| SNPH
    style SNPH fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (7)

Target	Relation	Type	Str
Alzheimer	expressed_in	disease	0.65
Ms	expressed_in	disease	0.65
Als	expressed_in	disease	0.65
MIRO1	expressed_in	gene	0.60
APP	expressed_in	gene	0.60
Mitophagy	expressed_in	pathway	0.60
PRESENILIN	expressed_in	gene	0.60

Incoming (3)

Source	Relation	Type	Str
APP	expressed_in	gene	0.60
MITOPHAGY	expressed_in	gene	0.60
ALZHEIMER'S DISEASE	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found