concept

TEMOZOLOMIDE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TEMOZOLOMIDE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

25Connections

0Hypotheses

0Analyses

9Outgoing

7Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	TEMOZOLOMIDE
Key Genes/Proteins	GPX4, SLC16A1, UBIQUITIN
Related Diseases	GLIOBLASTOMA, FERROPTOSIS, CELL DEATH, GLIOMA

Wiki Pages (8)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    TEMOZOLOMIDE["TEMOZOLOMIDE"]
    TEMOZOLOMIDE -->|"treats"| glioblastoma["glioblastoma"]
    TEMOZOLOMIDE -->|"regulates"| miR_519a["miR-519a"]
    TEMOZOLOMIDE -->|"treats"| glioma["glioma"]
    TEMOZOLOMIDE -->|"inhibits"| GLIOBLASTOMA["GLIOBLASTOMA"]
    Ytx_7739["Ytx-7739"] -->|"interacts"| TEMOZOLOMIDE
    CBD["CBD"] -->|"interacts"| TEMOZOLOMIDE
    miR_519a -->|"regulates"| TEMOZOLOMIDE
    autophagy["autophagy"] -->|"interacts"| TEMOZOLOMIDE
    GPX4["GPX4"] -->|"activates"| TEMOZOLOMIDE
    SLC16A1["SLC16A1"] -->|"target for"| TEMOZOLOMIDE

Outgoing (13)

Target	Relation	Type	Str
GLIOBLASTOMA	inhibits	disease	0.65
GLIOBLASTOMA	modifies	disease	0.65
GLIOBLASTOMA	associated_with	disease	0.45
FERROPTOSIS	associated_with	phenotype	0.45
GPX4	associated_with	gene	0.45
FLUOXETINE	associated_with	drug	0.45
CELL DEATH	associated_with	phenotype	0.45
UBIQUITIN	associated_with	protein	0.45
GLIOMA	associated_with	disease	0.45

Incoming (12)

Source	Relation	Type	Str
GPX4	activates	gene	0.65
SLC16A1	therapeutic_target	gene	0.60
FERROPTOSIS	associated_with	phenotype	0.45
GLIOBLASTOMA	associated_with	disease	0.45
GPX4	associated_with	gene	0.45
CELL DEATH	associated_with	phenotype	0.45
FLUOXETINE	associated_with	drug	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

TEMOZOLOMIDE

Understanding Entity Pages

Wiki Pages (8)

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