Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CELL APOPTOSIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CELL APOPTOSIS |
Knowledge base pages for this entity
graph TD
CELL_APOPTOSIS["CELL APOPTOSIS"]
CELL_APOPTOSIS -->|"causes"| Intervertebral_Disc_Degenerati["Intervertebral Disc Degeneration"]
CELL_APOPTOSIS -->|"contributes to"| Osteoarthritis["Osteoarthritis"]
CELL_APOPTOSIS -->|"contributes to"| Radiation_Induced_Intestinal_I["Radiation-Induced Intestinal Injury"]
LUZP1["LUZP1"] -->|"inhibits"| CELL_APOPTOSIS
NPC1["NPC1"] -->|"promotes"| CELL_APOPTOSIS
BCL_2["BCL-2"] -->|"inhibits"| CELL_APOPTOSIS
NF__B["NF-kappaB"] -->|"regulates"| CELL_APOPTOSIS
G3BP1["G3BP1"] -->|"regulates"| CELL_APOPTOSIS
Bcl_2["Bcl-2"] -->|"regulates"| CELL_APOPTOSIS
curcumin["curcumin"] -->|"inhibits"| CELL_APOPTOSIS
Hippo_pathway["Hippo pathway"] -->|"regulates"| CELL_APOPTOSIS| Target | Relation | Type | Str |
|---|---|---|---|
| Intervertebral Disc Degeneration | causes | disease | 0.85 |
| Radiation-Induced Intestinal Injury | contributes_to | disease | 0.85 |
| Osteoarthritis | contributes_to | disease | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| LUZP1 | inhibits | protein | 0.90 |
| NPC1 | promotes | gene | 0.90 |
| BCL-2 | inhibits | protein | 0.90 |
| Benzene, Toluene, and Xylene (BTX) | associated_with | compound | 0.85 |
| Hydroxyl Free Radicals | causes | compound | 0.85 |
| STAT3 | promotes | protein | 0.85 |
| NF-κB | regulates | protein | 0.85 |
| Triptolide | associated_with | drug | 0.82 |
| Curcumin | associated_with | drug | 0.82 |
| Helicobacter pylori | associated_with | entity | 0.80 |
| G3BP1 | regulates | protein | 0.80 |
| Bcl-2 | regulates | protein | 0.80 |
| Anti-apoptotic Agents | inhibits | drug | 0.80 |
| Buyang Huanwu Decoction | suppresses | compound | 0.80 |
| curcumin | inhibits | drug | 0.70 |
| Hippo pathway | regulates | pathway | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||