concept

EVEROLIMUS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EVEROLIMUS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections

0Hypotheses

1Analyses

13Outgoing

2Incoming

0Experiments

1Debates

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💡 Concept Info

Name	EVEROLIMUS
Key Genes/Proteins	MTOR, PI3K
Related Diseases	EPILEPSY

Pathway Diagram

graph TD
    EVEROLIMUS[EVEROLIMUS]
    EVEROLIMUS -->|inhibits| MTOR[MTOR]
    EVEROLIMUS -->|treats| epilepsy[epilepsy]
    EVEROLIMUS -->|treats| Tuberous_Sclerosis_Complex_Ass[Tuberous Sclerosis Complex-Associated Refractory Seizures]
    EVEROLIMUS -->|inhibits| mTOR[mTOR]
    EVEROLIMUS -->|treats| Drug_Resistant_Seizures[Drug-Resistant Seizures]

Outgoing (13)

Target	Relation	Type	Str
MTOR	inhibits	gene	0.95
mTOR	inhibits	protein	0.90
Seizure Frequency	associated_with	phenotype	0.90
Tuberous Sclerosis Complex-Associated Refractory Seizures	treats	disease	0.90
epilepsy	treats	disease	0.90
Drug-Resistant Seizures	treats	phenotype	0.85
cognitive function	improves	phenotype	0.70
PALBOCICLIB	associated_with	drug	0.45
RIBOCICLIB	associated_with	drug	0.45
PI3K	associated_with	gene	0.45
RAPAMYCIN	associated_with	drug	0.45
EPILEPSY	associated_with	disease	0.45
MTOR	associated_with	gene	0.45

Incoming (2)

Source	Relation	Type	Str
PALBOCICLIB	associated_with	drug	0.45
EPILEPSY	associated_with	disease	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

Which specific metabolic pathways in APOE4 microglia are causally linked to dysf

neurodegeneration | 2026-04-11 | 0 hypotheses

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (1)

Multi-agent debates referencing this entity

The debate identified glycolytic shifts and mTOR disruption but couldn't disting

closed · Rounds: 4 · Score: 0.48 · 2026-04-21

Related Research

Hypotheses and analyses mentioning EVEROLIMUS in their description or question text

No additional research found