lysosomal_function

Understanding Entity Pages

This page aggregates everything SciDEX knows about lysosomal_function: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

A mechanism referenced in 1 knowledge graph relationship. Key connections: GCase (protein) maintains.

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flowchart TD
    N0["Lysosomal Function"]
    N1["GRN"]
    N1 -->|"involved in"| N0
    N2["Alzheimer's Disease"]
    N0 -->|"involved in"| N2
    N3["Lyso-ChR2"]
    N3 -->|"modulates"| N0
    N4["Urolithin A"]
    N4 -->|"associated with"| N0
    N5["APOE4"]
    N5 -.->|"inhibits"| N0
    N6["CTSD"]
    N6 -->|"regulates"| N0
    N7["TFEB"]
    N7 -->|"regulates"| N0
    N8["Lyso-Chr2"]
    N8 -->|"regulates"| N0
    N9["LRRK2 Inhibitors"]
    N9 -->|"treats"| N0
    N10["MS4A4A"]
    N10 -.->|"inhibits"| N0
    N11["TMEM175"]
    N11 -->|"regulates"| N0

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 gene
    class N2 disease
    class N3 protein
    class N5 protein
    class N6 gene
    class N7 protein
    class N8 protein
    class N10 gene
    class N11 protein