cerebral-small-vessel-disease

Understanding Entity Pages

This page aggregates everything SciDEX knows about cerebral-small-vessel-disease: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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flowchart TD
    N0["Cerebral Small Vessel Disease"]
    N1["Lacunar Stroke"]
    N0 -->|"causes"| N1
    N2["Intracerebral Hemorrhage"]
    N0 -->|"causes"| N2
    N3["Vascular Cognitive Impairment"]
    N0 -->|"causes"| N3
    N4["Amyloid"]
    N4 -->|"causes"| N0
    N5["Arteriolosclerosis"]
    N5 -->|"contributes to"| N0
    N6["Cerebral Amyloid Angiopathy"]
    N6 -->|"contributes to"| N0
    N7["White Matter Hyperintensities"]
    N7 -->|"biomarker for"| N0
    N8["Lacunar Infarcts"]
    N8 -->|"biomarker for"| N0
    N9["Cognitive Impairment"]
    N0 -->|"causes"| N9
    N10["Parkinsonism"]
    N0 -->|"associated with"| N10
    N11["Depression"]
    N0 -->|"causes"| N11
    N12["Apathy"]
    N0 -->|"causes"| N12
    N13["Gait Disturbance"]
    N0 -->|"causes"| N13
    N14["Ion Channel Dysfunction"]
    N14 -->|"causes"| N0

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 disease
    class N5 disease
    class N6 disease
    class N14 mechanism