Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MICROTUBULE STABILITY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MICROTUBULE STABILITY |
| Linked Hypotheses | 2 hypotheses |
Knowledge base pages for this entity
graph TD
MICROTUBULE_STABILITY["MICROTUBULE STABILITY"]
MICROTUBULE_STABILITY -->|"involved_in"| Nervous_System_Development["Nervous System Development"]
MICROTUBULE_STABILITY -->|"involved_in"| Nervous_System_Maintenance["Nervous System Maintenance"]
MICROTUBULE_STABILITY -->|"regulates"| Neuronal_Cytoskeletal_Architec["Neuronal Cytoskeletal Architecture"]
MAPT["MAPT"] -->|"inhibits"| MICROTUBULE_STABILITY
MAP6["MAP6"] -->|"activates"| MICROTUBULE_STABILITY
MAP6_Rich_Microtubule_Domains["MAP6-Rich Microtubule Domains"] -->|"correlates_with"| MICROTUBULE_STABILITY
TAU["TAU"] -->|"modulates"| MICROTUBULE_STABILITY| Target | Relation | Type | Str |
|---|---|---|---|
| NEURODEGENERATION | associated_with | entity | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| HDAC6 Selective Inhibition to Restore Acetylation Balance an | 0.577 | structural biology | What is the atomic-resolution structure |
| HDAC6 Inhibition for Dual Restoration of Microtubule Stabili | 0.459 | neurodegeneration | Which tau PTMs are both disease-specific |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||