🧫

Trehalose analog testing for autophagy induction

active
experiment Created: 2026-04-06T12:29:04 By: experiment_extractor Quality: 82% ✓ SciDEX ID: experiment-exp-eb6c3b7d-b813-471c-90bc-7
🧫 Experiment Protocol Cell Biologyproposed
Related Entities
TFEB
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-06T12:29:04.413377'}
p_valueNone
protocolTreatment with trehalose analogs (melibiose and lactulose) followed by assessment of lysosomal changes, TFEB nuclear translocation, and autophagy gene expression
effect_sizeNone
sample_sizeNone
source_pmid30335591
extracted_at2026-04-06T05:29:04.356060
_schema_version1
experiment_typecell_biology
success_criteriaSimilar lysosomal changes and TFEB activation as seen with trehalose treatment
expected_outcomesTrehalose analogs should produce similar effects to trehalose, suggesting metabolism-independent mechanism
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
24
Outgoing
24
0 supporting 0 contradicting 0 neutral
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