🧫
Trehalose-induced lysosomal changes and TFEB activation
experiment
Created: 2026-04-06 12:29:04
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-b939a41c-0445-4658-bdaf-1
🧫 Experiment Protocol
Cell Biology
Related Entities
Metadata
| experiment_type | cell_biology |
| protocol | Cells treated with trehalose, followed by immunofluorescence analysis for TFEB localization and lysosomal markers, biochemical assays for PPP3/calcineurin activity, and measurement of lysosomal membra |
| expected_outcomes | Trehalose treatment should induce lysosomal changes leading to TFEB activation and autophagy upregulation |
| success_criteria | Significant TFEB nuclear translocation, lysosomal enlargement, and increased autophagy gene expression |
| sample_size | None |
| statistical_methods | None |
| p_value | None |
| effect_size | None |
| extracted_at | 2026-04-06T05:29:04.356050 |
| source_pmid | 30335591 |
| _origin | {'type': 'internal', 'url': None, 'tracked_at': '2026-04-06T12:29:04.358509'} |
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2 nodes, 1 edges
derives from (1)
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