gene 835 words KG: BACH1 2026-03-23
kind:genesection:genesstate:published
Contents

BACH1 — BTB Domain and CNC Homolog 1

🧬 Gene Info
Gene SymbolBACH1
Full NameBTB Domain and CNC Homolog 1
Chromosome21q21.3
Functionencodes a transcriptional repressor that competes with NRF2 for binding to antioxidant response elements (AREs) in the promoters of cytoprotective genes.
Primary ExpressionUbiquitous, high in brain, liver, spleen
PathwaysAkt, Apoptosis, Autophagy, Chaperone, Complement
UniProt IDO14867
NCBI Gene ID571
Ensembl IDENSG00000156273
OMIM602751
GeneCardsBACH1
Human Protein AtlasBACH1
InteractionsPKC, AKT, CUL3, FYN, NRF2, KEAP1
KG Connections156 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

BACH1 phosphorylates FYN
BACH1 phosphorylates NRF2
BACH1 activates PKC
BACH1 activates AKT
BACH1 activates CUL3
BACH1 regulates CUL3
BACH1 activates FYN
BACH1 regulates KEAP1
BACH1 activates NRF2
BACH1 regulates PI3K

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