gene 724 words KG: CHL1
Contents

CHL1 Gene

🧬 Gene Info
Gene SymbolCHL1
Full NameCHL1 Neural Cell Adhesion Molecule
Chromosome3p26.3
Functionencodes a neural cell adhesion molecule belonging to the L1 family of immunoglobulin superfamily CAMs.
Primary Expressionthe nervous system:
Molecular Weight200 kDa
Amino Acids209 aa
UniProt IDP0CAT4
NCBI Gene ID10752
Ensembl IDENSG00000113838
OMIM300114
GeneCardsCHL1
Human Protein AtlasCHL1
Extracellular domainContains 6 Ig-like domains and 5 fibronectin type III repeats, mediating homophilic and heterophilic interactions
Transmembrane domainSingle pass transmembrane region
Associated Diseasesneurodegeneration
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

TIMP1 associated_with CHL1
GATA2 therapeutic_target CHL1
PDGFRB associated_with CHL1
APP mediates CHL1
BACE1 co_mentioned CHL1
VPS35 regulates CHL1
BACE1 targets CHL1
CHL1 targets epilepsy
ALZHEIMER'S DISEASE therapeutic_target CHL1
IMMUNE INFILTRATION therapeutic_target CHL1

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