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Disease: Investment Landscape: Frontotemporal Dementia
disease
722 words
KG: ent-dise-f0561aeb
2026-03-25
kind:disease
section:diseases
state:published
Contents
Investment Landscape: Frontotemporal Dementia
Disease Info
PHASE1
34
PHASE1, PHASE2
12
PHASE2
46
PHASE2, PHASE3
3
PHASE3
12
PHASE4
8
NA
111
Not Applicable
144
RECRUITING
84
ACTIVE_NOT_RECRUITING
24
NOT_YET_RECRUITING
16
COMPLETED
172
Databases
OMIM
Orphanet
ClinicalTrials
PubMed
Knowledge Graph
Related Hypotheses (14)
Purinergic Signaling Polarization Control
Score: 0.55
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46
TREM2-Dependent Astrocyte-Microglia Cross-talk in Neurodegen
Score: 0.64
TREM2-Mediated Astrocyte-Microglia Cross-Talk in Neurodegene
Score: 0.61
Glymphatic-Mediated Tau Clearance Dysfunction
Score: 0.55
Dual-Circuit Tau Vulnerability Cascade
Score: 0.50
Dopaminergic Ventral Tegmental-Hippocampal Circuit Protectio
Score: 0.49
TREM2-mediated microglial tau clearance enhancement
Score: 0.49
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.41
TREM2-Dependent Microglial Senescence Transition
Score: 0.69
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.52
APOE-TREM2 Interaction Modulation
Score: 0.48
TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.43
Show 9 more
Related Analyses (12)
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
How do pathological stress granules in neurodegeneration esc
neurodegeneration · failed
RNA binding protein dysregulation across ALS FTD AD
neurodegeneration · failed
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed
Show 7 more
Related Experiments (8)
Down Syndrome Alzheimer's Disease: Mechanisms and Therapeuti
clinical · proposed · Score: 0.40
Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40
Tau depletion effects on neuronal development in primary cul
exploratory · proposed · Score: 0.90
Microtubule domain analysis in adult axons
exploratory · proposed · Score: 0.80
Pre-Symptomatic Tau Detection in MAPT Mutation Carriers
clinical · proposed · Score: 0.40
Microglial TREM2 Agonist In Vivo Efficacy
validation · proposed · Score: 0.40
TREM2 Agonist Therapy for Parkinson's Disease — Experimental
validation · proposed · Score: 0.40
TREM2 Function in Alzheimer's Disease — From Risk Variant to
validation · proposed · Score: 0.40
Show 3 more
See Also (15)
Yoga Therapy for Neurodegeneration
therapeutic · Pages share 3 hypotheses
YAP/TEAD Pathway Modulators for Neurodegeneration
therapeutic · Pages share 3 hypotheses
Wnt Signaling Modulators for Neurodegeneration
therapeutic · Pages share 3 hypotheses
vitamin-d-therapy-neurodegeneration
therapeutic · Pages share 3 hypotheses
Vitamin B Complex Therapy for Neurodegeneration
therapeutic · Pages share 3 hypotheses
VIP/VPAC Receptor Modulators for Neurodegeneration
therapeutic · Pages share 3 hypotheses
Vestibular and Balance Therapy for CBS/PSP
therapeutic · Pages share 3 hypotheses
VEGF and Angiogenesis Therapy
therapeutic · Pages share 3 hypotheses
Urolithin A for Neurodegeneration
therapeutic · Pages share 3 hypotheses
Urolithin A for Neurodegeneration
therapeutic · Pages share 3 hypotheses
tudca-udca-neurodegeneration
therapeutic · Pages share 3 hypotheses
TRPM8 Agonists for Neurodegeneration
therapeutic · Pages share 3 hypotheses
Triple Incretin Agonists (GLP-1/GIP/Glucagon) for Neuro
therapeutic · Pages share 3 hypotheses
TREM2 Agonist Therapy for Neurodegeneration
therapeutic · Pages share 3 hypotheses
Transcutaneous Vagal Nerve Stimulation (tVNS) for Parki
therapeutic · Pages share 3 hypotheses
Show 10 more