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entity 1,024 words KG: UBQLN2 2026-03-22
kind:entitysection:entitiesstate:published
Contents

UBQLN2 Protein (Ubiquilin-2)

Knowledge Graph

Related Hypotheses (4)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51Lysosomal Positioning Dynamics Modulation
Score: 0.43Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption
Score: 0.38

Related Analyses (5)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archivedProtein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archivedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archivedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

Related Experiments (2)

Netrin-1 and UNC5B knockdown effects on EMT in vitro
exploratory · proposed · Score: 0.85FTLD-Tau vs FTLD-TDP In Vivo Biomarker Differentiation
clinical · proposed · Score: 0.40

See Also (10)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activatesPackard Center for ALS Research
institution · KG edge: associated_withOPTN — Optineurin
gene · KG edge: associated_withC9orf72 — Chromosome 9 Open Reading Frame 72
gene · KG edge: associated_withGenes
index · KG edge: associated_with

Knowledge Graph (12 edges)

UBQLN2 activates PROTEIN_DEGRADATION
UBQLN2 associated_with OPTN
UBQLN2 associated_with GAIN
UBQLN2 associated_with C9ORF72
UBQLN2 interacts_with HSP70
UBQLN2 interacts_with UNC5B
UBQLN2 associated_with UBIQUITIN
UBQLN2 involved_in Protein Degradation
UBQLN2 activates TIA1
UBQLN2 activates HSPA1B
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