| Gene Symbol | OPTN |
| Full Name | Optineurin |
| Chromosome | 10p13 |
| Protein Type | Adaptor Protein |
| Function | is a 66 kDa coiled-coil domain-containing protein encoded by the OPTN gene on chromosome 10p13. |
| Primary Expression | Motor cortex, Spinal cord, Retina, Brain |
| Subcellular Localization | </strong></td><td>Cytoplasm, Golgi, mitochondria, nucleus</td></tr> |
| Molecular Weight | 66 kDa |
| Amino Acids | 577 aa |
| Pathways | Akt, Amyloid, Apoptosis, Autophagy, Immune Response |
| UniProt ID | Q96CV9 |
| NCBI Gene ID | 10133 |
| Ensembl ID | ENSG00000123240 |
| OMIM | 602432 |
| GeneCards | OPTN |
| Human Protein Atlas | OPTN |
| Associated Diseases | AD, ALI, ALS, AMI, AUTOPHAGY, AXONAL DEGENERATION |
| Known Drugs/Compounds | DEFERIPRONE, RAPAMYCIN, loganin, dimethyl fumarate, rapamycin |
| Interactions | RIPK1, ULK1, SMCR8, CALCOCO2, LC3, BECN1 |
| KG Connections | 2473 knowledge graph edges |
| Databases | GeneCardsHPASTRING |