gene 961 words KG: G3BP2
Contents

G3BP2 - Ras-GTPase-Activating Protein-Binding Protein 2

🧬 Gene Info
Gene SymbolG3BP2
Full NameRas-GTPase-Activating Protein-Binding Protein 2
AliasesPage for G3BP2, Page for G3BP2 Protein
Chromosome4p16.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight56 kDa
Amino Acids523 aa
PathwaysNF-κB, MAPK
UniProt ID[Q9UWR1](https://www.uniprot.org/uniprot/Q9UWR1)
Ensembl IDENSG00000138798
GeneCardsG3BP2
Human Protein AtlasG3BP2
RRM Domains (RNA Recognition Motifs)Two RRM domains (RRM1 and RRM2) for RNA binding
RG-rich RegionArginine-glycine rich region for protein-protein interactions
NTF2-like DomainMediates homodimerization and stress granule targeting
Associated DiseasesAls, Cancer
InteractionsCAPRIN1, G3BP1, Proteasome, RNA, TDP-43
KG Connections38 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

ALS-Associated G3BP1/2 Mutations Disrupt TRIM21 Binding Inte
Score: 0.58

Knowledge Graph (12 edges)

G3BP2 activates G3BP1
CAPRIN1 interacts_with G3BP2
G3BP2 inhibits G3BP1
G3BP2 associated_with G3BP1
G3BP2 interacts_with G3BP1
G3BP2 expressed_in Brainstem
G3BP1 activates G3BP2
G3BP1 regulates G3BP2
G3BP2 regulates TDP-43
G3BP1 inhibits G3BP2

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