| Gene Symbol | BBC3 |
| Full Name | BCL2 Binding Component 3 (PUMA) |
| Aliases | BBC3 gene encoding PUMA |
| Chromosome | 19q13.32 |
| Function | Unlike anti-apoptotic Bcl-2 proteins or pro-apoptotic Bax/Bak proteins, BH3-only proteins contain only the BH3 (Bcl-2 Homology 3) domain, which is essential for their pro-apoptotic function. |
| Amino Acids | 193 aa |
| UniProt ID | [Q9BXW1](https://www.uniprot.org/uniprotkb/Q9BXW1/entry) |
| Ensembl ID | ENSG00000100711 |
| GeneCards | BBC3 |
| Human Protein Atlas | BBC3 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | ATP |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |