gene 2,674 words KG: DCTN1 2026-03-25
kind:genesection:genesstate:publishedevidence:strong
Contents

DCTN1 (Dynactin Subunit 1)

🧬 Gene Info
Gene SymbolDCTN1
Full NameDynactin Subunit 1 (p150^Glued)
AliasesDynactin subunit p150^Glued
Protein FamilyDynactin complex
FunctionDCTN1 plays critical roles in neuronal function
Subcellular LocalizationCytoplasm, neuronal axons, growth cones
Molecular Weight150 kDa
Amino Acids238 aa
UniProt IDQ14203
GeneCardsDCTN1
Human Protein AtlasDCTN1
MutationPhenotype
p.P56LPerry syndrome
p.G59EPerry syndrome/PD
p.R155CPerry syndrome
Associated DiseasesALS, frontotemporal dementia
InteractionsDYNEIN, DYNACTIN, POLE, Dynein, LAMP2, MAP1LC3B
KG Connections42 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph