gene 591 words KG: LAPTM4B 2026-03-21
kind:genesection:genesstate:published
Contents

LAPTM4B Gene

🧬 Gene Info
Gene SymbolLAPTM4B
Full NameLysosomal Associated Transmembrane Protein 4 Beta
Chromosome2q21.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressioncancers and has been studied extensively as a cancer biomarker
Amino Acids347 aa
Pathwaysmtor, mTOR
UniProt ID[Q9Y5G5](https://www.uniprot.org/uniprot/Q9Y5G5)
Ensembl IDENSG00000167996
GeneCardsLAPTM4B
Human Protein AtlasLAPTM4B
Membrane integrationMultiple transmembrane domains anchor it in lysosomal membranes
Lysosomal traffickingParticipates in vesicular transport to and from lysosomes
Autophagy supportContributes to autophagosome-lysosome fusion events
Cell cycle regulationModulates cell cycle progression
Associated Diseasesneurodegeneration
InteractionsHDAC2, AUTOPHAGY, AND, CANCER, LYSOSOME
KG Connections23 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph