gene 3,191 words KG: LMX1B
Contents

LMX1B Gene

🧬 Gene Info
Gene SymbolLMX1B
Chromosome9q33.3
Protein TypeTranscription Factor
Functionencodes a critical transcription factor required for the proper development and maintenance of dopaminergic neurons in the midbrain.
Molecular Weight~41 kDa
Amino Acids372 aa
Exons5
PathwaysAlpha-Synuclein, Er Stress, Synaptic Plasticity
UniProt IDO43823
NCBI Gene ID4010
Ensembl IDENSG00000136944
OMIM602575
GeneCardsLMX1B
Human Protein AtlasLMX1B
FeatureDetails
Associated DiseasesParkinson
KG Connections35 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (9)

Digital Twin-Guided Metabolic Reprogramming
Score: 0.61
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.48
Correcting Gut Microbial Dopamine Imbalance to Support Syste
Score: 0.41
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.48
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47

Related Analyses (8)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived

See Also (11)

PGC-1α (PPARGC1A)
protein · KG edge: regulates
ER Stress and Unfolded Protein Response in Corticobasal
mechanism · KG edge: regulates
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: regulates
SNCA — Alpha-Synuclein
gene · KG edge: regulates
SFPQ Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

LMX1B associated_with NURR1
LMX1B regulates SNCA
LMX1B regulates PINK1
LMX1B regulates SFPQ
LMX1B regulates NFM
LMX1B regulates HNRNPA1
LMX1B regulates PGC1ALPHA
LMX1B regulates PARK7
LMX1B co_expressed_with NFM
LMX1B co_expressed_with NURR1