| Gene Symbol | LRP10 |
| Protein Type | Receptor |
| Function | LRP10 is a transmembrane receptor protein involved in |
| Primary Expression | neurons and has been implicated in endosomal-lysosomal trafficking and protein clearance pathways |
| GeneCards | LRP10 |
| Human Protein Atlas | LRP10 |
| Aspect | Details |
| Inheritance | Risk factor (complex inheritance) |
| Variants | Multiple rare coding variants identified |
| Mechanism | Impaired protein clearance, endosomal dysfunction |
| Population | Found in multiple ethnic groups |
| Disease | Relationship |
| Progressive Supranuclear Palsy | Some LRP10 associations reported |
| Frontotemporal Dementia | Possible role in protein clearance |
| Multiple System Atrophy | Under investigation |
| Associated Diseases | Parkinson's disease |
| Interactions | APP, SORL1, ALZHEIMER'S DISEASE, ENDOSOMES |
| KG Connections | 31 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |