| Gene Symbol | REST |
| Full Name | RE1-Silencing Transcription Factor |
| Chromosome | 4q12 |
| Protein Type | Transcription Factor |
| Function | REST (also known as NRSF) is a zinc-finger transcription factor that represses neuronal gene expression in non-neuronal cells and regulates synaptic plasticity in neurons. |
| Pathways | Autophagy, Circadian Rhythm, Epigenetic, Immune Response, Lipid Metabolism |
| UniProt ID | Q9Y2W1 |
| NCBI Gene ID | 5978 |
| Ensembl ID | ENSG00000100647 |
| OMIM | 600571 |
| GeneCards | REST |
| Human Protein Atlas | REST |
| Associated Diseases | Aging, Als, Alzheimer, Alzheimer's disease, Ataxia, Atherosclerosis |
| Interactions | CD2AP, NRF2, P38, CREB1, PPARGC1A, REELIN |
| KG Connections | 334 knowledge graph edges |
| Databases | GeneCardsHPASTRING |