| Gene Symbol | PBX3 |
| Full Name | Pre-B-cell Leukemia Homeobox 3 |
| Chromosome | 9q33.3 |
| Function | encodes a member of the TALE (Three Amino Acid Loop Extension) family of homeodomain transcription factors. |
| Molecular Weight | 47 kDa |
| Amino Acids | 430 aa |
| Pathways | Wnt, Notch, BMP effectors |
| UniProt ID | [P40417](https://www.uniprot.org/uniprot/P40417) |
| Ensembl ID | ENSG00000167081 |
| OMIM | 176076 |
| GeneCards | PBX3 |
| Human Protein Atlas | PBX3 |
| Homeodomain | The DNA-binding helix-turn-helix motif (residues 239-299) |
| TALE domain | The three-amino-acid loop extension between helices 1 and 2 of the homeodomain |
| Transactivation domain | Located in the N-terminal region |
| Associated Diseases | neurodegeneration |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |