Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MICRORNAS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
MICRORNAS is a gene implicated in neurodegeneration research. Key relationships include: regulates, therapeutic target, associated with. Associated with ALS, Aging, Als. Connected to 1072 entities in the SciDEX knowledge graph.
| Gene Symbol | MICRORNAS |
| Primary Expression | Ca1, Hippocampus, Prefrontal Cortex, Cortex, Thalamus |
| Pathways | Apoptosis, Immune Response, Microrna, Differentiation, Stem Cell |
| GeneCards | MICRORNAS |
| Human Protein Atlas | MICRORNAS |
| Associated Diseases | ALS, Aging, Alzheimer, Amyotrophic Lateral Sclerosis, Asthma |
| Interactions | MIRNAS, TNF, LDLR, SLC16A2, VDR, RAB27A |
| KG Connections | 1594 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
MICRORNAS["MICRORNAS"] -->|"therapeutic target"| Cancer["Cancer"]
MICRORNAS["MICRORNAS"] -->|"regulates"| Alzheimer["Alzheimer"]
MICRORNAS["MICRORNAS"] -->|"activates"| Aging["Aging"]
MICRORNAS["MICRORNAS"] -.->|"inhibits"| Cancer_1["Cancer"]
MICRORNAS["MICRORNAS"] -->|"activates"| Tumor["Tumor"]
MICRORNAS["MICRORNAS"] -->|"activates"| Ms["Ms"]
ACSL5["ACSL5"] -->|"therapeutic target"| MICRORNAS["MICRORNAS"]
SLC16A2["SLC16A2"] -->|"therapeutic target"| MICRORNAS["MICRORNAS"]
JUN["JUN"] -->|"therapeutic target"| MICRORNAS["MICRORNAS"]
GSS["GSS"] -->|"therapeutic target"| MICRORNAS["MICRORNAS"]
style MICRORNAS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| Cancer | therapeutic_target | disease | 1.00 |
| Cancer | regulates | disease | 1.00 |
| Als | therapeutic_target | disease | 1.00 |
| Inflammation | therapeutic_target | disease | 1.00 |
| Cancer | expressed_in | disease | 1.00 |
| Als | expressed_in | disease | 1.00 |
| Tumor | expressed_in | disease | 1.00 |
| Apoptosis | therapeutic_target | pathway | 1.00 |
| Tumor | therapeutic_target | disease | 1.00 |
| GENES | regulates | gene | 1.00 |
| Als | associated_with | disease | 1.00 |
| Als | activates | disease | 1.00 |
| Inflammation | regulates | disease | 1.00 |
| Epigenetic | regulates | pathway | 1.00 |
| Als | regulates | disease | 1.00 |
| Tumor | regulates | disease | 1.00 |
| Apoptosis | regulates | pathway | 1.00 |
| Immune Response | regulates | pathway | 1.00 |
| Alzheimer | associated_with | disease | 1.00 |
| Obesity | regulates | disease | 1.00 |
| INFLAMMATION | regulates | gene | 1.00 |
| Microrna | regulates | pathway | 1.00 |
| Differentiation | regulates | pathway | 1.00 |
| Mapk | regulates | pathway | 1.00 |
| Microrna | associated_with | pathway | 1.00 |
| Metastasis | therapeutic_target | pathway | 1.00 |
| Microrna | therapeutic_target | pathway | 1.00 |
| Microrna | activates | pathway | 1.00 |
| Microrna | implicated_in | pathway | 1.00 |
| Microrna | expressed_in | pathway | 1.00 |
| Microrna | inhibits | pathway | 1.00 |
| Aging | regulates | disease | 1.00 |
| NEUROINFLAMMATION | regulates | gene | 1.00 |
| Neuroinflammation | regulates | disease | 1.00 |
| Atherosclerosis | regulates | disease | 1.00 |
| Lipid Metabolism | regulates | pathway | 1.00 |
| GENES | therapeutic_target | gene | 1.00 |
| Angiogenesis | regulates | pathway | 1.00 |
| Differentiation | activates | pathway | 1.00 |
| Cholesterol | regulates | pathway | 1.00 |
| Alzheimer | regulates | disease | 0.95 |
| Inflammation | associated_with | disease | 0.95 |
| Neurodegeneration | regulates | disease | 0.95 |
| Cardiovascular | regulates | disease | 0.95 |
| Cancer | associated_with | disease | 0.95 |
| Als | implicated_in | disease | 0.95 |
| Inflammation | activates | disease | 0.95 |
| Als | treats | disease | 0.95 |
| Infection | regulates | disease | 0.95 |
| Diabetes | regulates | disease | 0.95 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CANCER | expressed_in | gene | 1.00 |
| CANCER | therapeutic_target | gene | 1.00 |
| MIRNAS | expressed_in | gene | 1.00 |
| MIRNAS | therapeutic_target | gene | 1.00 |
| MIRNAS | regulates | gene | 1.00 |
| INFLAMMATION | regulates | gene | 1.00 |
| APOPTOSIS | therapeutic_target | gene | 1.00 |
| CANCER | regulates | gene | 1.00 |
| APOPTOSIS | regulates | gene | 1.00 |
| MIRNAS | associated_with | gene | 1.00 |
| MIRNAS | implicated_in | gene | 1.00 |
| GENES | regulates | gene | 1.00 |
| MIRNAS | contributes_to | gene | 1.00 |
| INFLAMMATION | therapeutic_target | gene | 1.00 |
| PI3K | activates | gene | 1.00 |
| PI3K | regulates | gene | 1.00 |
| MIRNAS | inhibits | gene | 1.00 |
| GENES | therapeutic_target | gene | 0.90 |
| OXIDATIVE STRESS | therapeutic_target | gene | 0.90 |
| STAT3 | regulates | gene | 0.90 |
| NEURODEGENERATIVE DISEASES | therapeutic_target | gene | 0.90 |
| NEURODEGENERATION | regulates | gene | 0.90 |
| CYTOKINES | regulates | gene | 0.90 |
| CANCER | associated_with | gene | 0.90 |
| MIRNAS | activates | gene | 0.90 |
| CANCER | activates | gene | 0.90 |
| Hub Mirgs | interacts_with | biomarker | 0.85 |
| GENES | activates | gene | 0.80 |
| NF-ΚB | regulates | gene | 0.80 |
| NEURODEGENERATIVE DISEASES | regulates | gene | 0.80 |
| NEURODEGENERATION | activates | gene | 0.80 |
| ALZHEIMER | regulates | gene | 0.80 |
| TNF | regulates | gene | 0.80 |
| ALZHEIMER | associated_with | gene | 0.80 |
| GENES | associated_with | gene | 0.80 |
| OXIDATIVE STRESS | regulates | gene | 0.80 |
| CANCER | implicated_in | gene | 0.80 |
| INFLAMMATION | activates | gene | 0.80 |
| PI3K | therapeutic_target | gene | 0.70 |
| PI3K | expressed_in | gene | 0.70 |
| DNA | therapeutic_target | gene | 0.70 |
| BCL2 | regulates | gene | 0.70 |
| AUTOPHAGY | regulates | gene | 0.70 |
| NF-ΚB | expressed_in | gene | 0.70 |
| P53 | regulates | gene | 0.70 |
| CANCER | inhibits | gene | 0.70 |
| TP53 | regulates | gene | 0.70 |
| CYTOKINES | therapeutic_target | gene | 0.70 |
| PARKINSON'S DISEASE | therapeutic_target | gene | 0.70 |
| ERK | associated_with | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||