gene 1,257 words KG: PLCB1 2026-03-25
kind:genesection:genestopic:alzheimerstopic:parkinsons
Contents

PLCB1 Gene

🧬 Gene Info
Gene SymbolPLCB1
Full NamePhospholipase C Beta 1
Chromosome20p12.3
Functionencodes phospholipase C beta 1, a critical enzyme in the phosphoinositide signaling pathway
UniProt IDQ9NQ66
NCBI Gene ID23236
Ensembl IDENSG00000141642
OMIM607120
GeneCardsPLCB1
Human Protein AtlasPLCB1
Protein NamePhospholipase C beta 1 (PLC-β1)
IsoformDistribution
PLCB1aNeurons, widespread
PLCB1bTestis, some brain regions
Receptor FamilyExamples
Associated DiseasesALS, Alzheimer
Known Drugs/Compoundsaducanumab
InteractionsCD81, GDI2, CAPZB, NDUFS7, NDUFA4, Proteins
KG Connections46 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph