| Gene Symbol | RAD50 |
| Full Name | DNA Repair Protein RAD50 |
| Chromosome | 5q23.2 |
| Protein Family | SMC family (Structural Maintenance of Chromosomes) |
| Function | encodes a crucial DNA repair protein that serves as the structural scaffold of the MRN complex (MRE11-RAD50-NBS1), which is essential for recognizing and repairing DNA double-strand breaks (DSBs). |
| Subcellular Localization | Nucleus (chromatin-associated) |
| Molecular Weight | 180 kDa |
| Amino Acids | 1586 aa |
| Gene Type | Protein coding |
| UniProt ID | Q9XQB3 |
| NCBI Gene ID | 10111 |
| Ensembl ID | ENSG00000113522 |
| OMIM | 604040 |
| GeneCards | RAD50 |
| Human Protein Atlas | RAD50 |
| Associated Diseases | neurodegeneration |
| Interactions | DRP1, RAD52, TBP |
| SciDEX Hypotheses | MRN Complex-PIC Interaction Disruptors |
| KG Connections | 5 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!